Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 5/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491342 | 1.00 | GHSR (0.53) | GHSROPRM1GAAMAPTHTT | |
| SCHEMBL8790279 | 0.92 | MAPT (0.46) | GHSROPRM1GAAMAPTHTT | |
| SCHEMBL6481968 | 0.89 | HDAC8 (0.44) | GHSROPRM1GAAMAPTHTT | |
| SCHEMBL6480650 | 0.88 | GHSR (0.51) | GHSROPRM1ACE | |
| SCHEMBL6484182 | 0.87 | MMP1 (0.50) | GAAMAPTHTTCTSLTACR1 | |
| SCHEMBL8790317 | 0.86 | GHSR (0.61) | GHSROPRM1GAAMAPTHTT | |
| SCHEMBL8790623 | 0.85 | MMP2 (0.44) | GAAMAPTHTTCTSLCTSS | |
| SCHEMBL8790632 | 0.85 | MMP2 (0.44) | GAAMAPTHTTCTSLCTSS | |
| SCHEMBL8789119 | 0.84 | MAPT (0.44) | GAAMAPTHTTCTSLCTSS | |
| SCHEMBL6495989 | 0.84 | MAPT (0.45) | GAAMAPTHTTCTSLTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669830-A4 | SUBSTITUTED DIPEPTIDE ANALOGS PROMOTE RELEASE OF GROWTH HORMONE. | MERCK & CO INC (US) | 1997-02-26 | — | — | EP | claimed |
| EP-0669830-A1 | SUBSTITUTED DIPEPTIDE ANALOGS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO. INC. (US) | 1995-09-06 | — | — | EP | claimed |
| WO-1994011012-A1 | SUBSTITUTED DIPEPTIDE ANALOGS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1994-05-26 | — | — | WO | claimed |
| WO-1994011012-A1 | SUBSTITUTED DIPEPTIDE ANALOGS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1994-05-26 | — | — | WO | disclosed |