Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.39 |
| ▸ | AKT1 | P31749 | 3/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8792580 | 0.85 | AGTR1 (0.32) | LTB4R2AKT1 | |
| SCHEMBL8789378 | 0.76 | CTSS (0.42) | ADRB2CASRMEN1KMT2A | |
| SCHEMBL8792444 | 0.73 | AGTR1 (0.36) | LTB4R2ADRB2ADRB1ADRB3 | |
| SCHEMBL8791543 | 0.72 | ADRB2 (0.35) | LTB4R2ADRB2ADRB1ADRB3FFAR1 | |
| SCHEMBL9421648 | 0.72 | PSMB5 (0.44) | ADRB2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8791072 | 0.72 | PSMB5 (0.44) | ADRB2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8789114 | 0.71 | AGTR1 (0.34) | LTB4R2AKT1 | |
| SCHEMBL8789185 | 0.70 | — | — | |
| SCHEMBL8791116 | 0.69 | CTSS (0.39) | CASRMEN1KMT2A | |
| SCHEMBL8791113 | 0.69 | CTSS (0.39) | CASRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669830-A4 | SUBSTITUTED DIPEPTIDE ANALOGS PROMOTE RELEASE OF GROWTH HORMONE. | MERCK & CO INC (US) | 1997-02-26 | — | — | EP | claimed |
| EP-0669830-A1 | SUBSTITUTED DIPEPTIDE ANALOGS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO. INC. (US) | 1995-09-06 | — | — | EP | claimed |