Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8973452 | 0.99 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4CKMT2AGAA | |
| SCHEMBL8792739 | 0.86 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4CKMT2AGAA | |
| SCHEMBL8790380 | 0.86 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4CKMT2AGAA | |
| SCHEMBL8790903 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4CKMT2AGAA | |
| SCHEMBL8790745 | 0.77 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4CKMT2AHDAC6 | |
| SCHEMBL8791432 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4CKMT2AHSD11B1 | |
| SCHEMBL8791414 | 0.76 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4CKMT2A | |
| SCHEMBL8790955 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4CKMT2AHSD11B1 | |
| SCHEMBL9690737 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4CKMT2AHSD11B1 | |
| SCHEMBL8790565 | 0.76 | ALDH1A1 (0.43) | ALDH1A1HPGDKMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421365-B1 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | WAKAMOTO PHARMA CO LTD (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0421365-A2 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1991-04-10 | — | — | EP | disclosed |