Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8790045 | 0.80 | KMT2A (0.63) | ALDH1A1HPGDKMT2AKDM4CHDAC6 | |
| SCHEMBL8947097 | 0.79 | ALDH1A1 (0.60) | ALDH1A1HPGDHSD11B1KDM4CHDAC6 | |
| SCHEMBL8947261 | 0.78 | ALDH1A1 (0.75) | ALDH1A1HPGDHSD11B1KDM4CHDAC6 | |
| SCHEMBL5966693 | 0.77 | ALDH1A1 (0.74) | ALDH1A1HPGDHSD11B1KDM4CHDAC6 | |
| SCHEMBL8947331 | 0.77 | ALDH1A1 (0.84) | ALDH1A1HPGDHSD11B1KDM4CHDAC6 | |
| SCHEMBL8790380 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HPGDKMT2AHSD11B1KDM4C | |
| SCHEMBL8792739 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HPGDKMT2AHSD11B1KDM4C | |
| SCHEMBL8790883 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HPGDKMT2AHSD11B1KDM4C | |
| SCHEMBL8791432 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HPGDKMT2AHSD11B1KDM4C | |
| Hydrochloric Acid SCHEMBL8973452 | 0.75 | ALDH1A1 (0.51) | ALDH1A1HPGDKMT2AHSD11B1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506011-A1 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-30 | — | — | EP | disclosed |