Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6037538 | 0.88 | IDO1 (0.42) | MEN1KMT2AACHEL3MBTL1HPGD | |
| SCHEMBL7244019 | 0.84 | TSHR (0.44) | MEN1KMT2AACHEL3MBTL1HPGD | |
| SCHEMBL27495785 | 0.83 | PTGER1 (0.41) | MEN1KMT2AACHEPTGER1L3MBTL1 | |
| SCHEMBL6037511 | 0.82 | TSHR (0.42) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL5155305 | 0.82 | GAA (0.49) | KMT2AACHEPTGER1ALDH1A1LMNA | |
| SCHEMBL6037570 | 0.81 | TP53 (0.38) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL1954826 | 0.80 | SIGMAR1 (0.44) | ACHEHPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10424602 | 0.78 | CA1 (0.50) | KMT2AALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL6037550 | 0.78 | MTNR1A (0.50) | PTGER1L3MBTL1ALDH1A1MAPTHTT | |
| SCHEMBL6210311 | 0.76 | L3MBTL1 (0.41) | MEN1KMT2APTGER1L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805796-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1997-11-12 | — | — | EP | claimed |
| WO-1996022966-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1996-08-01 | — | — | WO | claimed |