SCHEMBL8791967

SCHEMBL8791967

CC(N)C(=O)N1CCC(CC(=O)O)CC1(C)C

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 6/20 0.36
ITGA2B P08514 6/20 0.36
ANPEP P15144 1/20 0.35
ENPEP Q07075 1/20 0.35
ARG1 P05089 3/20 0.33
DPP4 P27487 3/20 0.33
DPP7 Q9UHL4 3/20 0.33
FAP Q12884 2/20 0.33
DPP8 Q6V1X1 2/20 0.33
PREP P48147 1/20 0.33
DPP9 Q86TI2 1/20 0.33
ARG2 P78540 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8791960 1.00 ITGB3 (0.36) ITGB3ITGA2BANPEPENPEPARG1
SCHEMBL8790914 0.85 BRD4 (0.34) DPP4DPP7FAPDPP8PREP
SCHEMBL8790582 0.78 CYP2C19 (0.41) DPP4DPP7PREP
SCHEMBL19502859 0.77 DPP4 (0.37) DPP4DPP7FAPDPP8PREP
SCHEMBL8792779 0.75 ITGB3 (0.52) ITGB3ITGA2BANPEPENPEPDPP7
SCHEMBL8792886 0.75 ITGB3 (0.52) ITGB3ITGA2BANPEPENPEPDPP7
SCHEMBL8791958 0.73 ITGB3 (0.36) ITGB3ITGA2BANPEPENPEP
SCHEMBL17328054 0.73 KDM4E (0.38)
SCHEMBL21244367 0.66 ARG1 (0.35) ARG1ARG2
SCHEMBL7938014 0.66 SLC6A12 (0.35) ANPEPENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0800516-A1 FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME NIPPON STEEL CORPORATION (JP) 1997-10-15 EP disclosed