Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4571036 | 0.71 | HSD17B10 (0.71) | HSD17B10HPGDKDM4ETSHRHTT | |
| SCHEMBL30464743 | 0.71 | HSD17B10 (0.71) | HSD17B10HPGDKDM4ETSHRHTT | |
| SCHEMBL6131393 | 0.70 | PTGS2 (0.41) | HPGDTSHRHTTMEN1KMT2A | |
| SCHEMBL4963145 | 0.68 | TSHR (0.46) | KDM4ETSHRHTTMAPTALDH1A1 | |
| SCHEMBL7998630 | 0.67 | TSHR (0.38) | KDM4ETSHRHTTMEN1KMT2A | |
| SCHEMBL9750717 | 0.66 | IDO1 (0.61) | HSD17B10HPGDKDM4ETSHRMEN1 | |
| SCHEMBL3440796 | 0.66 | ADRA2C (0.72) | HSD17B10HPGDKDM4ETSHRHTT | |
| SCHEMBL22738460 | 0.66 | HSD17B10 (0.59) | HSD17B10HPGDKDM4ETSHRHTT | |
| SCHEMBL12681587 | 0.66 | TSHR (0.38) | TSHRHTTCYP3A4ALDH1A1TDP1 | |
| SCHEMBL4571038 | 0.66 | HSD17B10 (0.63) | HSD17B10HPGDKDM4ETSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620809-B1 | $g(a)-SUBSTITUTED BENZENEMETHANAMINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 1997-03-05 | — | — | EP | disclosed |