Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26115642 | 0.79 | TSHR (0.57) | TSHRPKMHTTLMNARECQL | |
| SCHEMBL12680684 | 0.71 | GABRA1 (0.38) | TSHRLMNASMN1; SMN2 | |
| SCHEMBL31561701 | 0.71 | LMNA (0.39) | TSHRLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6131393 | 0.71 | PTGS2 (0.41) | TSHRHTTLMNATDP1MEN1 | |
| SCHEMBL11810264 | 0.70 | TSHR (0.50) | TSHRPKMHTTLMNARECQL | |
| SCHEMBL23341753 | 0.67 | TSHR (0.55) | TSHRPKMHTTLMNARECQL | |
| SCHEMBL4089395 | 0.67 | TSHR (0.55) | TSHRPKMHTTLMNARECQL | |
| SCHEMBL22624549 | 0.67 | TSHR (0.55) | TSHRPKMHTTLMNARECQL | |
| SCHEMBL8790915 | 0.67 | HSD17B10 (0.45) | TSHRHTTKDM4ETDP1MEN1 | |
| SCHEMBL23862186 | 0.67 | TSHR (0.43) | TSHRPKMHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008032-A1 | CATALYST LIGANDS USEFUL FOR CROSS-COUPLING REACTIONS | SYMYX TECHNOLOGIES, INC. (US) | 2000-02-17 | — | — | WO | disclosed |