Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340652 | 0.79 | RAB9A (0.50) | RECQLRAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL16719986 | 0.79 | RECQL (0.55) | KMT2ARECQLRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL7356569 | 0.79 | RECQL (0.73) | KMT2ARECQLRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL8791401 | 0.76 | KMT2A (0.57) | MEN1KMT2ARECQLRAB9ASMN1; SMN2 | |
| SCHEMBL2530939 | 0.73 | RECQL (0.50) | RECQLRAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL292960 | 0.72 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2PGRALDH1A1 | |
| SCHEMBL8790936 | 0.70 | SMN1; SMN2 (0.81) | RECQLRAB9ASMN1; SMN2L3MBTL1PGR | |
| SCHEMBL8631856 | 0.70 | KMT2A (0.66) | MEN1KMT2AALDH1A1OPRM1OPRL1 | |
| SCHEMBL13116697 | 0.70 | RECQL (0.57) | RECQLRAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL11203413 | 0.68 | KMT2A (0.56) | MEN1KMT2ASMN1; SMN2ALDH1A1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800516-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1997-10-15 | — | — | EP | disclosed |