Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8790929 | 0.79 | MEN1 (0.56) | RECQLRAB9ASMN1; SMN2HSD11B1L3MBTL1 | |
| SCHEMBL16719986 | 0.79 | RECQL (0.55) | RECQLRAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL13116697 | 0.77 | RECQL (0.57) | RECQLRAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL8791401 | 0.76 | KMT2A (0.57) | RECQLRAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL2530939 | 0.73 | RECQL (0.50) | RECQLRAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL292679 | 0.72 | HSD11B1 (0.46) | RECQLSMN1; SMN2HSD11B1PGRALDH1A1 | |
| SCHEMBL8791216 | 0.70 | SMN1; SMN2 (0.81) | RECQLRAB9ASMN1; SMN2HSD11B1L3MBTL1 | |
| SCHEMBL8632730 | 0.70 | ALOX5 (0.50) | SMN1; SMN2HSD11B1ALDH1A1MGLLMAPT | |
| SCHEMBL704636 | 0.69 | HSD11B1 (0.46) | RECQLHSD11B1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL20103479 | 0.67 | HSD11B1 (0.51) | HSD11B1L3MBTL1ALDH1A1MAPTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800516-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996020172-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED β-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1996-07-04 | — | — | WO | disclosed |