Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 16/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8791256 | 0.84 | ALDH1A1 (0.66) | MCHR1HRH3KDM4E | |
| SCHEMBL5432297 | 0.83 | MCHR1 (0.62) | MCHR1HRH3 | |
| SCHEMBL4850684 | 0.81 | MCHR1 (0.61) | MCHR1HRH3 | |
| SCHEMBL5423752 | 0.81 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL11679191 | 0.81 | KDM4E (0.81) | MCHR1HRH3KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11676911 | 0.80 | KDM4E (0.79) | MCHR1KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8790307 | 0.80 | HTR1A (0.60) | MCHR1KDM4EL3MBTL1 | |
| SCHEMBL11677718 | 0.79 | KDM4E (0.79) | MCHR1KDM4EL3MBTL1 | |
| SCHEMBL6071591 | 0.79 | HRH3 (1.00) | MCHR1HRH3 | |
| Trifluoroacetic Acid SCHEMBL6799476 | 0.78 | MCHR1 (0.60) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560235-B1 | Condensed heterocyclic ketone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-06-04 | — | — | EP | disclosed |
| US-5462934-A | Cholinesterase inhibitor; learning enhancement | TAKEDA CHEMICAL INDUSTRIES (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0560235-A1 | Condensed heterocyclic ketone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1993-09-15 | — | — | EP | disclosed |