SCHEMBL7204552

SCHEMBL7204552

C=Cn1ccc(=O)[nH]c1=O

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.48
DDB1 Q16531 1/20 0.44
PKM P14618 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
DUT P33316 4/20 0.33
SLC28A1 O00337 1/20 0.32
SLC28A2 O43868 1/20 0.32
SLC29A1 Q99808 1/20 0.32
SLC28A3 Q9HAS3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10694738 0.77 CRBN (0.47) CRBNDDB1PKML3MBTL1ALDH1A1
SCHEMBL7715133 0.77 CRBN (0.47) CRBNDDB1PKML3MBTL1ALDH1A1
SCHEMBL7715134 0.77 CRBN (0.47) CRBNDDB1PKML3MBTL1ALDH1A1
SCHEMBL7984568 0.75 CRBN (0.45) CRBNDDB1PKML3MBTL1ALDH1A1
SCHEMBL9486307 0.72 CRBN (0.47) CRBNDDB1PKMDUTSLC28A1
SCHEMBL9486303 0.72 CRBN (0.47) CRBNDDB1PKMDUTSLC28A1
SCHEMBL4537742 0.69 DUT (0.49) CRBNPKML3MBTL1ALDH1A1LMNA
SCHEMBL3425729 0.68
SCHEMBL1398237 0.68 CRBN (0.42) CRBNDDB1PKMALDH1A1LMNA
SCHEMBL9266208 0.67 CRBN (0.41) CRBNDDB1PKMDUTSLC28A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181213-A Polymer for adsorbing metal ions and application thereof 深圳市康益保健用品有限公司 2022-10-14 CN claimed
CN-111269355-A Polymer containing heterocyclic structure and application thereof 深圳市康益保健用品有限公司 2020-06-12 CN claimed
JP-59184211-A None JP disclosed
CN-117186101-A Preparation method of monohydroxycyclopropane nucleoside analogue 云南贵金属实验室有限公司 2023-12-08 CN disclosed
CN-117186100-A Preparation method of vinyl cyclopropane nucleoside analogue 云南贵金属实验室有限公司 2023-12-08 CN disclosed
CN-111303612-B Blue-light-proof polyurethane optical resin material 万华化学集团股份有限公司 2022-02-15 CN disclosed
CN-108314655-B Method for synthesizing three-membered carbocyclic pyrimidine nucleoside analogue through rhodium-catalyzed asymmetric cyclopropanation 河南师范大学 2021-01-15 CN disclosed
CN-111518232-A Polymer added with heterocyclic compound, composition and application of composition 深圳市康益保健用品有限公司 2020-08-11 CN disclosed
CN-111303612-A Blue-light-proof polyurethane optical resin material 万华化学集团股份有限公司 2020-06-19 CN disclosed
CN-111269355-A Polymer containing heterocyclic structure and application thereof 深圳市康益保健用品有限公司 2020-06-12 CN disclosed
CN-108314655-A A kind of method of rhodium catalysis asymmetry ciprofloxacin eye drops synthesis of ternary carbocyclic ring pyrimidine nucleoside analoys 河南师范大学 2018-07-24 CN disclosed
CN-1420773-A 5-(E)-bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use UNIV YALE (US) 2003-05-28 CN disclosed
US-6020374-A INSULIN MIMICS RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) 2000-02-01 US disclosed
US-5858296-A A BIOLOGICALLY ACTIVE MOLECULE FORMED BY POLYMERIZATION OF FUNCTIONAL MONOMERS AROUND A TEMPLATE MOLECULE THAT EXHIBITS DRUG ACTIVITY, REMOVAL OF TEMPLATE AND POLYMERIZATION OF SECOND CLASS OF MONOMER IN THE VOIDS LEFT BY TEMPLATE YISSUM RESEARCH DEVELOPMENT CO. OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1999-01-12 US disclosed
US-5630978-A POLYMERIZATION OF FUNCTIONAL MONOMERS AROUND A BIOLOGICALLY ACTIVE TEMPLATE MOLECULE, REMOVAL OF TEMPLATE TO LEAVE A VOID, THEN POLYMERIZATION OF OTHER MONOMER(S) IN THE VOID YISSUM RESEARCH DEVELOPMENT CO. OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1997-05-20 US disclosed
WO-1996040822-A1 PREPARATION OF BIOLOGICALLY ACTIVE MOLECULES BY MOLECULAR IMPRINTING YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (US) 1996-12-19 WO disclosed
EP-0402272-B1 Cell-culturing substrate, cell-culturing substrate unit bioreactor and extracorporeal circulation type therapeutic apparatus TERUMO CORP (JP) 1995-10-04 EP disclosed
EP-0402272-A2 Cell-culturing substrate, cell-culturing substrate unit bioreactor and extracorporeal circulation type therapeutic apparatus TERUMO KABUSHIKI KAISHA (JP) 1990-12-12 EP disclosed
US-4740314-A Anionic polymers containing N-vinyl-2-pyrrolidone or other vinyl amides and maleic anhydride or maleic acid as scale inhibitors for preventing or reducing calcium phosphate and other scales NALCO CHEMICAL COMPANY (US) 1988-04-26 US disclosed
JP-S59184211-A HIGH-RIGIDITY RESIN COMPOSITION MATSUSHITA ELECTRIC IND CO LTD 1984-10-19 JP disclosed