Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5922043 | 0.90 | PDK2 (0.32) | PDK2PSEN1PSEN2APH1BNCSTN | |
| Oxalic Acid SCHEMBL9703375 | 0.82 | PDK2 (0.35) | PDK2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9049720 | 0.82 | PDK2 (0.34) | PDK2PSEN1PSEN2APH1BNCSTN | |
| Oxalic Acid SCHEMBL9702508 | 0.74 | PDK2 (0.38) | PDK2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8790855 | 0.71 | HSD11B1 (0.46) | — | |
| SCHEMBL9050211 | 0.69 | — | — | |
| SCHEMBL19271805 | 0.68 | PSEN1 (0.37) | PDK2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL19189060 | 0.68 | PDK2 (0.36) | PDK2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8790627 | 0.66 | ALDH1A1 (0.30) | — | |
| SCHEMBL8790767 | 0.65 | HSD11B1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413545-B1 | Azabicyclic compounds | BEECHAM GROUP PLC (GB) | 1997-05-14 | — | — | EP | claimed |
| EP-0413545-A2 | Azabicyclic compounds | Beecham Group p.l.c. (GB) | 1991-02-20 | — | — | EP | claimed |