Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | OGG1 | O15527 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10856983 | 0.80 | NOTUM (0.56) | TP53ALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL8792645 | 0.79 | NOTUM (0.56) | TP53ALDH1A1LMNAHPGDAVPR2 | |
| SCHEMBL5418837 | 0.79 | ALDH1A1 (0.49) | TP53ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL5417050 | 0.77 | ALDH1A1 (0.47) | TP53ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL7487677 | 0.76 | TP53 (0.52) | TP53ALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL7488125 | 0.75 | TP53 (0.44) | TP53ALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL3082421 | 0.75 | NOTUM (0.62) | TP53ALDH1A1LMNAMAPTOGG1 | |
| SCHEMBL8791620 | 0.74 | TP53 (0.43) | TP53ALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL9206324 | 0.73 | ACHE (0.58) | — | |
| SCHEMBL15828391 | 0.72 | ALDH1A1 (0.52) | ALDH1A1LMNANPSR1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560235-B1 | Condensed heterocyclic ketone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-06-04 | — | — | EP | disclosed |
| US-5462934-A | Cholinesterase inhibitor; learning enhancement | TAKEDA CHEMICAL INDUSTRIES (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0560235-A1 | Condensed heterocyclic ketone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1993-09-15 | — | — | EP | disclosed |