Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | FAAH | O00519 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406930 | 0.93 | MAPK1 (0.48) | SIGMAR1ACHEMAPK1 | |
| SCHEMBL8409570 | 0.78 | MAPK1 (0.50) | SIGMAR1ACHEMAPK1 | |
| SCHEMBL8409924 | 0.78 | ACHE (0.49) | ACHE | |
| SCHEMBL8406904 | 0.76 | ACHE (0.52) | ACHEBCHE | |
| SCHEMBL8409521 | 0.76 | DRD2 (0.61) | SIGMAR1ACHEMAPK1 | |
| SCHEMBL8408438 | 0.75 | DRD2 (0.50) | SIGMAR1ACHE | |
| SCHEMBL8406491 | 0.74 | ACHE (0.50) | ACHE | |
| SCHEMBL8409920 | 0.74 | DRD2 (0.48) | SIGMAR1ACHE | |
| SCHEMBL8406869 | 0.74 | CXCR4 (0.75) | ACHECXCR4 | |
| SCHEMBL8791696 | 0.74 | MAPK1 (0.48) | SIGMAR1ACHEMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797576-A1 | ALKYL SUBSTITUTED PIPERADINYL AND PIPERAZINYL ANTI-AIDS COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 1997-10-01 | — | — | EP | disclosed |