Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8791209 | 0.93 | SIGMAR1 (0.46) | MAPK1ACHESIGMAR1 | |
| SCHEMBL8409570 | 0.84 | MAPK1 (0.50) | MAPK1ACHESIGMAR1KMT2APOLB | |
| SCHEMBL8406904 | 0.82 | ACHE (0.52) | ACHE | |
| SCHEMBL8409521 | 0.81 | DRD2 (0.61) | MAPK1ACHESIGMAR1KMT2APOLB | |
| SCHEMBL8408438 | 0.81 | DRD2 (0.50) | ACHESIGMAR1 | |
| SCHEMBL8791696 | 0.80 | MAPK1 (0.48) | MAPK1ACHESIGMAR1KMT2AMEN1 | |
| SCHEMBL8409924 | 0.80 | ACHE (0.49) | ACHE | |
| SCHEMBL8791235 | 0.80 | ACHE (0.49) | ACHE | |
| SCHEMBL8406480 | 0.79 | DRD2 (0.53) | MAPK1ACHESIGMAR1KMT2APOLB | |
| SCHEMBL8408645 | 0.78 | MAPK1 (0.51) | MAPK1ACHESIGMAR1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866589-A | Alkyl substituted piperadinyl and piperazinyl anti-AIDS compounds | PHARMACIA & UPJOHN COMPANY (US) | 1999-02-02 | — | — | US | disclosed |
| EP-0797576-A1 | ALKYL SUBSTITUTED PIPERADINYL AND PIPERAZINYL ANTI-AIDS COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018628-A1 | ALKYL SUBSTITUTED PIPERADINYL AND PIPERAZINYL ANTI-AIDS COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 1996-06-20 | — | — | WO | disclosed |