Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844713 | 0.79 | ALDH1A1 (0.44) | PTPN1 | |
| SCHEMBL842959 | 0.76 | PTPN1 (0.34) | PTPN1 | |
| SCHEMBL843602 | 0.76 | PTPN1 (0.36) | PTPN1 | |
| SCHEMBL844309 | 0.74 | GABRP (0.36) | — | |
| SCHEMBL6666033 | 0.73 | — | — | |
| SCHEMBL6663022 | 0.73 | IKBKE (0.32) | — | |
| SCHEMBL24665757 | 0.71 | KCNJ1 (0.33) | — | |
| SCHEMBL29268229 | 0.66 | BRD4 (0.37) | — | |
| SCHEMBL10293443 | 0.65 | MTNR1A (0.42) | PTPN1 | |
| SCHEMBL15912346 | 0.62 | PTPN1 (0.55) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432707-B1 | AZABICYCLIC-SUBSTITUTED FUSED-HETEROARYL COMPOUNDS FOR THE TREATMENT OF DISEASE | PHARMACIA & UPJOHN CO LLC (US) | 2012-03-28 | — | — | EP | disclosed |