Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409570 | 0.84 | MAPK1 (0.50) | MAPK1NPSR1ACHEMAPTPKM | |
| SCHEMBL8791281 | 0.83 | OPRM1 (0.42) | ACHEKMT2AMEN1SIGMAR1BACE1 | |
| SCHEMBL8406485 | 0.82 | MAPK1 (0.46) | MAPK1NPSR1ACHEFAAHMAPT | |
| SCHEMBL8791942 | 0.81 | ACHE (0.50) | MAPK1NPSR1ACHEFAAHMAPT | |
| SCHEMBL8791219 | 0.80 | OPRM1 (0.43) | ACHECHRM2CHRM3KMT2AMEN1 | |
| SCHEMBL9091787 | 0.79 | CHRM2 (0.42) | ACHECHRM2KMT2AMEN1SIGMAR1 | |
| SCHEMBL8406812 | 0.77 | CHRM2 (0.43) | MAPK1ACHECHRM2CHRM3SIGMAR1 | |
| SCHEMBL8791696 | 0.77 | MAPK1 (0.48) | MAPK1NPSR1ACHEMAPTPKM | |
| SCHEMBL8792306 | 0.76 | ACHE (0.39) | ACHEKMT2AMEN1SIGMAR1BCHE | |
| SCHEMBL9092805 | 0.75 | SCN1A (0.39) | ACHECHRM2CHRM3BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797576-A1 | ALKYL SUBSTITUTED PIPERADINYL AND PIPERAZINYL ANTI-AIDS COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018628-A1 | ALKYL SUBSTITUTED PIPERADINYL AND PIPERAZINYL ANTI-AIDS COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 1996-06-20 | — | — | WO | disclosed |