Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.64 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8793373 | 0.83 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL462 | 0.83 | AGTR2 (0.80) | AGTR1AGTR2 | |
| SCHEMBL265 | 0.80 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL7318777 | 0.79 | AGTR1 (0.71) | AGTR1AGTR2 | |
| SCHEMBL8792974 | 0.79 | AGTR2 (0.70) | AGTR1AGTR2 | |
| SCHEMBL760 | 0.78 | AGTR2 (0.78) | AGTR1AGTR2 | |
| SCHEMBL1426 | 0.77 | AGTR2 (0.62) | AGTR1AGTR2 | |
| SCHEMBL8792660 | 0.77 | AGTR2 (0.70) | AGTR1AGTR2 | |
| SCHEMBL753 | 0.77 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL8790099 | 0.77 | AGTR1 (0.61) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652869-B1 | IMIDAZOLE ETHERS HAVING A II ANTAGONIST ACTIVITY | LUSO FARMACO INST (IT) | 1997-03-26 | — | — | EP | disclosed |
| EP-0652869-A1 | IMIDAZOLE ETHERS HAVING A II ANTAGONIST ACTIVITY. | LUSO FARMACO INST (IT) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994002467-A1 | IMIDAZOLE ETHERS HAVING A II ANTAGONIST ACTIVITY | INSTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1994-02-03 | — | — | WO | disclosed |