Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 11/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30205674 | 0.83 | TDP1 (0.56) | CTSKCTSSCTSLCTSBKDM4E | |
| SCHEMBL29436139 | 0.83 | TDP1 (0.56) | CTSKCTSSCTSLCTSBKDM4E | |
| SCHEMBL30070636 | 0.80 | TDP1 (0.53) | MEN1KMT2ACTSKCTSLCTSB | |
| Hydrochloric Acid SCHEMBL9300196 | 0.80 | POLB (0.50) | MEN1KMT2AAAK1KDM4EALDH1A1 | |
| SCHEMBL30070627 | 0.79 | MMP3 (0.52) | CTSKCTSLCTSBMMP1MMP3 | |
| SCHEMBL29419657 | 0.79 | SIRT5 (0.54) | MEN1KMT2ACTSKCTSLMMP1 | |
| SCHEMBL15569405 | 0.79 | SIRT5 (0.54) | MEN1KMT2ACTSKCTSLMMP1 | |
| SCHEMBL29742197 | 0.79 | SIRT5 (0.54) | MEN1KMT2ACTSKCTSLMMP1 | |
| SCHEMBL29419659 | 0.79 | SIRT5 (0.54) | MEN1KMT2ACTSKCTSLMMP1 | |
| SCHEMBL3364435 | 0.77 | RAB9A (0.53) | KMT2ACTSKMMP1MMP3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516532-B1 | Watersoluble coumarin derivatives, their preparation and their use as enzyme substrates or for the preparation of those substrates | EUROBIO LAB (FR) | 1997-01-15 | — | — | EP | disclosed |
| US-5342970-A | Hydrosoluble coumarin derivatives, their preparation and their use as an enzyme substrate or for the preparation of such substrates | LABORATOIRES EUROBIO (FR) | 1994-08-30 | — | — | US | disclosed |
| EP-0516532-A1 | Watersoluble coumarin derivatives, their preparation and their use as enzyme substrates or for the preparation of those substrates | LABORATOIRES EUROBIO (FR) | 1992-12-02 | — | — | EP | disclosed |