Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 13/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1255819 | 0.87 | ADORA2A (0.60) | L3MBTL1KDM4EALDH1A1POLBMEN1 | |
| SCHEMBL1255923 | 0.86 | L3MBTL1 (0.54) | L3MBTL1KDM4EALDH1A1POLBMEN1 | |
| SCHEMBL1255858 | 0.86 | KDM4E (0.62) | L3MBTL1KDM4EALDH1A1POLBMEN1 | |
| SCHEMBL1256305 | 0.84 | L3MBTL1 (0.57) | L3MBTL1KDM4EALDH1A1POLBMEN1 | |
| SCHEMBL1257189 | 0.84 | L3MBTL1 (0.49) | L3MBTL1KDM4EALDH1A1POLBMEN1 | |
| SCHEMBL1254692 | 0.83 | KDM4E (0.49) | L3MBTL1KDM4EALDH1A1POLBMEN1 | |
| SCHEMBL1257072 | 0.83 | L3MBTL1 (0.62) | L3MBTL1KDM4EALDH1A1POLBMEN1 | |
| SCHEMBL1677411 | 0.83 | ADORA2A (0.48) | L3MBTL1KDM4EALDH1A1POLBMEN1 | |
| SCHEMBL1255678 | 0.82 | ALDH1A1 (0.52) | L3MBTL1KDM4EALDH1A1POLBMEN1 | |
| SCHEMBL1257008 | 0.82 | L3MBTL1 (0.50) | L3MBTL1KDM4EALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1921077-B1 | AGENT FOR TREATING AND/OR PREVENTING SLEEP DISORDER | KYOWA HAKKO KIRIN CO LTD (JP) | 2017-07-26 | — | — | EP | disclosed |
| EP-3002283-B1 | THIAZOLE DERIVATIVES | KYOWA HAKKO KIRIN CO LTD (JP) | 2017-06-14 | — | — | EP | disclosed |
| EP-3002283-A1 | THIAZOLE DERIVATIVES | Kyowa Hakko Kirin Co., Ltd. (JP) | 2016-04-06 | — | — | EP | disclosed |
| EP-1700856-B1 | THIAZOLE DERIVATIVE | KYOWA HAKKO KIRIN CO LTD (JP) | 2015-11-11 | — | — | EP | disclosed |
| EP-2433938-A1 | THERAPEUTIC AGENT FOR MOTOR DISORDERS | Kyowa Hakko Kirin Co., Ltd. (JP) | 2012-03-28 | — | — | EP | disclosed |