SCHEMBL1255858

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1256305	0.94	L3MBTL1 (0.57)	KDM4EALDH1A1POLBL3MBTL1MEN1
	SCHEMBL1255923	0.91	L3MBTL1 (0.54)	KDM4EALDH1A1POLBL3MBTL1MEN1
	SCHEMBL1255855	0.91	ALDH1A1 (0.71)	KDM4EALDH1A1POLBL3MBTL1MEN1
	SCHEMBL1256301	0.91	ALDH1A1 (0.75)	KDM4EALDH1A1POLBL3MBTL1MEN1
	SCHEMBL1257072	0.88	L3MBTL1 (0.62)	KDM4EALDH1A1POLBL3MBTL1MEN1
	SCHEMBL1257087	0.88	ALDH1A1 (0.53)	KDM4EALDH1A1POLBL3MBTL1MEN1
	SCHEMBL1255819	0.88	ADORA2A (0.60)	KDM4EALDH1A1POLBL3MBTL1MEN1
	SCHEMBL1255678	0.87	ALDH1A1 (0.52)	KDM4EALDH1A1POLBL3MBTL1MEN1
	SCHEMBL1257008	0.87	L3MBTL1 (0.50)	KDM4EALDH1A1POLBL3MBTL1MEN1
	SCHEMBL1254692	0.86	KDM4E (0.49)	KDM4EALDH1A1POLBL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.