Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308110 | 0.94 | FOLH1 (0.47) | FOLH1PIN1OPRD1KMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL8793852 | 0.91 | OPRK1 (0.46) | OPRD1KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL7749727 | 0.83 | OPRK1 (0.48) | KMT2AMEN1ALDH1A1L3MBTL1ANPEP | |
| SCHEMBL8439130 | 0.76 | FNTA (0.63) | FOLH1KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL7751346 | 0.76 | FNTA (0.63) | FOLH1KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL24130549 | 0.74 | PIN1 (0.55) | PIN1OPRD1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7788436 | 0.73 | FOLH1 (0.56) | FOLH1PIN1KMT2AMEN1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL29443957 | 0.70 | KMT2A (0.48) | KMT2AMEN1ALDH1A1ANPEPMAPT | |
| Trifluoroacetic Acid SCHEMBL20454604 | 0.70 | KMT2A (0.48) | KMT2AMEN1ALDH1A1ANPEPMAPT | |
| Trifluoroacetic Acid SCHEMBL20454605 | 0.70 | KMT2A (0.48) | KMT2AMEN1ALDH1A1ANPEPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783518-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO. INC. (US) | 1997-07-16 | — | — | EP | disclosed |