SCHEMBL8794745

SCHEMBL8794745

CO[SiH](CC1CCCCC1)OC.CO[Si](OC)(c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.34
ALDH1A1 P00352 1/20 0.34
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
NPC1 O15118 2/20 0.32
MAPT P10636 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
VCP P55072 1/20 0.32
EPHX2 P34913 1/20 0.31
HPGD P15428 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SLC6A4 P31645 2/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
ATM Q13315 1/20 0.30
SLC6A2 P23975 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6057468 0.86 MEN1 (0.30) RAB9AMEN1KMT2AMAPTNPSR1
SCHEMBL6689627 0.77 CYP1A2 (0.36)
SCHEMBL145494 0.77 CYP1A2 (0.36)
SCHEMBL249519 0.75 CYP1A2 (0.32)
SCHEMBL8794751 0.72 ALDH1A1 (0.34) RAB9AALDH1A1SLC6A4SLC6A2
Ethyl Benzoate SCHEMBL17530708 0.71 CHRNB2 (0.45) RAB9AALDH1A1MEN1KMT2ANPC1
SCHEMBL27978836 0.71
SCHEMBL27539053 0.71 SLC6A2 (0.31) ALDH1A1MEN1KMT2ASLC6A4SLC6A2
SCHEMBL966700 0.71
SCHEMBL49008 0.71 CA4 (0.41) RAB9AALDH1A1MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0584586-B1 Process for preparing a polypropylene wax HOECHST AG (DE) 1997-05-07 EP disclosed
EP-0584586-A2 Process for preparing a polypropylene wax HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-02 EP disclosed