Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAT2A | P31153 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8794407 | 0.94 | CDH1 (0.48) | DHODHGAAALDH1A1CYP2C9PTGES | |
| SCHEMBL8795005 | 0.90 | DHODH (0.50) | DHODHGAAALDH1A1CYP2C9PTGES | |
| SCHEMBL8794037 | 0.89 | DHODH (0.50) | DHODHGAAALDH1A1CYP2C9KMT2A | |
| SCHEMBL8794203 | 0.89 | DHODH (0.44) | DHODHGAAALDH1A1CYP2C9PTGES | |
| SCHEMBL8795287 | 0.88 | DHODH (0.48) | DHODHLMNASMN1; SMN2 | |
| SCHEMBL8794351 | 0.86 | DHODH (0.49) | DHODHALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL8794864 | 0.86 | KDM4E (0.50) | DHODHGAAMAPTLMNAKDM4E | |
| SCHEMBL8795058 | 0.85 | DHODH (0.48) | DHODHGAAALDH1A1KMT2AHPGD | |
| SCHEMBL8794498 | 0.85 | DHODH (0.67) | DHODHALDH1A1POLBKMT2AKDM4E | |
| SCHEMBL8794990 | 0.84 | DHODH (0.51) | DHODHKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379145-B1 | Substituted quinolinecarboxylic acids | AMERICAN CYANAMID CO (US) | 1997-05-07 | — | — | EP | claimed |