Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CDH1 | P12830 | 1/20 | 0.42 |
| ▸ | APC | P25054 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8794990 | 0.90 | DHODH (0.51) | LMNAPDE10ADHODH | |
| SCHEMBL8794407 | 0.86 | CDH1 (0.48) | GAAAKR1B10DHODHCDH1APC | |
| SCHEMBL8794800 | 0.86 | DHODH (0.56) | KDM4ELMNAGAAL3MBTL1MAPT | |
| SCHEMBL8795029 | 0.85 | SCN9A (0.57) | KDM4ELMNAMAPTDHODH | |
| SCHEMBL8795106 | 0.82 | DHODH (0.48) | DHODH | |
| SCHEMBL8794037 | 0.80 | DHODH (0.50) | GAAAKR1B10DHODHCDH1APC | |
| SCHEMBL8794203 | 0.80 | DHODH (0.44) | GAAAKR1B10DHODHCDH1APC | |
| SCHEMBL8795287 | 0.79 | DHODH (0.48) | LMNADHODH | |
| SCHEMBL8793224 | 0.79 | DHODH (0.58) | KDM4ELMNAGAAL3MBTL1PDE10A | |
| SCHEMBL8795005 | 0.79 | DHODH (0.50) | GAADHODHCDH1APCCTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379145-B1 | Substituted quinolinecarboxylic acids | AMERICAN CYANAMID CO (US) | 1997-05-07 | — | — | EP | claimed |