Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 19/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795901 | 0.88 | DHODH (0.46) | DHODHDHFRALKBH5 | |
| SCHEMBL8794800 | 0.88 | DHODH (0.56) | DHODHLMNASMN1; SMN2 | |
| SCHEMBL8795106 | 0.87 | DHODH (0.48) | DHODHDHFRALKBH5 | |
| SCHEMBL8794407 | 0.86 | CDH1 (0.48) | DHODH | |
| SCHEMBL8795005 | 0.85 | DHODH (0.50) | DHODH | |
| SCHEMBL8793368 | 0.85 | DHODH (0.48) | DHODHDHFRALKBH5 | |
| SCHEMBL8792397 | 0.84 | DHODH (0.62) | DHODHDHFRALKBH5 | |
| SCHEMBL8794037 | 0.82 | DHODH (0.50) | DHODH | |
| SCHEMBL8794203 | 0.82 | DHODH (0.44) | DHODH | |
| SCHEMBL8794864 | 0.79 | KDM4E (0.50) | DHODHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379145-B1 | Substituted quinolinecarboxylic acids | AMERICAN CYANAMID CO (US) | 1997-05-07 | — | — | EP | claimed |