Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8793241 | 0.99 | GLA (0.43) | GLACYP4F2CYP4A11KDM4EKDM4A | |
| SCHEMBL7160661 | 0.96 | GLA (0.45) | GLACYP4F2CYP4A11KDM4EKDM4A | |
| SCHEMBL8888011 | 0.78 | LTA4H (0.49) | CYP4F2CYP4A11 | |
| SCHEMBL6583573 | 0.78 | PPARG (0.54) | MAPTPPARGMAPK1SMN1; SMN2 | |
| SCHEMBL7164843 | 0.78 | ESR1 (0.42) | CYP4F2CYP4A11KDM4EPPARGHIF1A | |
| SCHEMBL8887955 | 0.78 | ESR1 (0.42) | CYP4F2CYP4A11KDM4EPPARGHIF1A | |
| SCHEMBL8889073 | 0.78 | ESR1 (0.42) | CYP4F2CYP4A11KDM4EPPARGHIF1A | |
| SCHEMBL8886986 | 0.78 | ESR1 (0.42) | CYP4F2CYP4A11KDM4EPPARGHIF1A | |
| SCHEMBL8888505 | 0.77 | MGLL (0.50) | CYP4F2CYP4A11 | |
| SCHEMBL8890354 | 0.77 | MGLL (0.50) | CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612743-B1 | Oxazolidinedione derivatives, their production and use in lowering blood sugar and lipid levels | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-09-10 | — | — | EP | disclosed |