Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | TLR3 | O15455 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796400 | 0.87 | ALDH1A1 (0.38) | ALDH1A1AKR1B1CA1CA2CA7 | |
| SCHEMBL27328716 | 0.82 | CA1 (0.38) | ALDH1A1KMT2AKDM4EMAPTAKR1B1 | |
| SCHEMBL8794145 | 0.81 | TP53 (0.38) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8794948 | 0.80 | ALDH1A1 (0.40) | ALDH1A1KMT2AMAPTHTTAKR1B1 | |
| SCHEMBL8308734 | 0.79 | AKR1B1 (0.43) | ALDH1A1KMT2AMAPTHTTTP53 | |
| SCHEMBL8795162 | 0.78 | SMN1; SMN2 (0.46) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8795244 | 0.78 | POLB (0.36) | ALDH1A1LMNAKMT2AKDM4EMAPT | |
| SCHEMBL27316930 | 0.77 | PRSS1 (0.40) | ALDH1A1CYP1A2CYP2C19KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL8796125 | 0.76 | ALDH1A1 (0.37) | ALDH1A1LMNAKMT2AKDM4EMAPT | |
| SCHEMBL8794716 | 0.76 | MAPT (0.38) | ALDH1A1KMT2AKDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541807-A1 | NOVEL BENZOPYRAN DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 1993-05-19 | — | — | EP | disclosed |