Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | ACR | P10323 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174966 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2TP53L3MBTL1PRSS1ACR | |
| SCHEMBL6283849 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2TP53L3MBTL1PRSS1ACR | |
| SCHEMBL27672005 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2TP53L3MBTL1PRSS1ACR | |
| SCHEMBL28281866 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2TP53L3MBTL1PRSS1ACR | |
| SCHEMBL11655269 | 0.83 | CYP4F2 (0.50) | SMN1; SMN2L3MBTL1RAB9ANPC1ALDH1A1 | |
| SCHEMBL7944868 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2TP53L3MBTL1PRSS1ACR | |
| SCHEMBL321520 | 0.82 | TSHR (0.52) | SMN1; SMN2TP53L3MBTL1RAB9ANPC1 | |
| SCHEMBL320845 | 0.82 | TSHR (0.52) | SMN1; SMN2TP53L3MBTL1RAB9ANPC1 | |
| SCHEMBL30744976 | 0.81 | LMNA (0.56) | SMN1; SMN2TP53L3MBTL1RAB9ANPC1 | |
| SCHEMBL7843721 | 0.81 | CES2 (0.44) | SMN1; SMN2L3MBTL1RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683781-A4 | NOVEL INHIBITORS OF ADENOSINE MONOPHOSPHATE DEAMINASE. | GENSIA PHARMA (US) | 1997-05-28 | — | — | EP | disclosed |
| EP-0683781-A1 | NOVEL INHIBITORS OF ADENOSINE MONOPHOSPHATE DEAMINASE | GENSIA PHARMACEUTICALS, INC. (US) | 1995-11-29 | — | — | EP | disclosed |