Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4114434 | 0.83 | HTR7 (0.67) | HTR7ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL8311251 | 0.82 | HTR7 (0.65) | HTR7ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL8318327 | 0.82 | HTR7 (0.65) | HTR7ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL9066035 | 0.82 | HTR6 (0.49) | HTR7ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL5016354 | 0.81 | HTR7 (0.67) | HTR7ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL9066402 | 0.81 | HTR6 (0.48) | HTR7ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL21900694 | 0.79 | HTR1B (0.81) | HTR7ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL4904410 | 0.77 | HTR1D (0.55) | HTR7ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL7407989 | 0.77 | HTR1D (0.55) | HTR7ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL10747672 | 0.76 | HTR1D (0.54) | HTR7ADRA2AADRA2BADRA2CNISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635491-B1 | (Thia) cycloalkyl(b)indoles, process of their preparation and compositions containing it | ADIR (FR) | 1997-05-07 | — | — | EP | claimed |
| EP-0635491-A1 | (Thia) cycloalkyl(b)indoles, process of their preparation and compositions containing it | ADIR ET COMPAGNIE (FR) | 1995-01-25 | — | — | EP | claimed |
| EP-0635491-B1 | (Thia) cycloalkyl(b)indoles, process of their preparation and compositions containing it | ADIR (FR) | 1997-05-07 | — | — | EP | disclosed |
| US-5491163-A | POWERFUL ANTIOXIDANT AND PROTECTS HUMAN LIPIDS, SPECIALLY LOW DENSITY LIPOPROTEINS | ADIR ET COMPAGNIE (FR) | 1996-02-13 | — | — | US | disclosed |
| EP-0635491-A1 | (Thia) cycloalkyl(b)indoles, process of their preparation and compositions containing it | ADIR ET COMPAGNIE (FR) | 1995-01-25 | — | — | EP | disclosed |