Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.31 |
| ▸ | MAPT | P10636 | 5/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795103 | 1.00 | AKR1B1 (0.34) | AKR1B1ABCC9MEN1KMT2AEGFR | |
| SCHEMBL8795892 | 0.87 | EGFR (0.34) | AKR1B1ABCC9MEN1KMT2AEGFR | |
| SCHEMBL8795889 | 0.87 | EGFR (0.34) | AKR1B1ABCC9MEN1KMT2AEGFR | |
| SCHEMBL8795381 | 0.80 | KMT2A (0.38) | AKR1B1ABCC9MEN1KMT2AEGFR | |
| SCHEMBL8794999 | 0.80 | EGFR (0.36) | AKR1B1ABCC9EGFRALDH1A1MAPT | |
| SCHEMBL8795895 | 0.79 | EGFR (0.34) | AKR1B1ABCC9MEN1KMT2AEGFR | |
| SCHEMBL8794786 | 0.76 | MEN1 (0.35) | AKR1B1ABCC9MEN1KMT2AEGFR | |
| SCHEMBL8794789 | 0.76 | MEN1 (0.35) | AKR1B1ABCC9MEN1KMT2AEGFR | |
| SCHEMBL9566804 | 0.76 | MAPT (0.36) | AKR1B1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL8316094 | 0.75 | TLR3 (0.35) | AKR1B1MEN1KMT2AEGFRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541807-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1997-12-17 | — | — | EP | disclosed |
| US-5412117-A | Potassium channel activators, antiasmatics, antiepileptics | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0541807-A1 | NOVEL BENZOPYRAN DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 1993-05-19 | — | — | EP | disclosed |