Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8794786 | 1.00 | MEN1 (0.35) | MEN1KMT2APOLBBCHEMALT1 | |
| SCHEMBL8316094 | 0.91 | TLR3 (0.35) | MEN1KMT2APOLBMALT1EGFR | |
| SCHEMBL8795892 | 0.86 | EGFR (0.34) | MEN1KMT2APOLBEGFRAKR1B1 | |
| SCHEMBL8795889 | 0.86 | EGFR (0.34) | MEN1KMT2APOLBEGFRAKR1B1 | |
| SCHEMBL8316173 | 0.82 | EGFR (0.34) | EGFRAKR1B1ALDH1A1MAPTMAPK1 | |
| SCHEMBL8313666 | 0.80 | TBXA2R (0.31) | MEN1KMT2AEGFRAKR1B1ALDH1A1 | |
| SCHEMBL8794707 | 0.79 | NR3C1 (0.32) | MALT1EGFRAKR1B1ALDH1A1NR3C1 | |
| SCHEMBL8796257 | 0.78 | ALDH1A1 (0.36) | MEN1KMT2AMALT1AKR1B1ALDH1A1 | |
| SCHEMBL8795103 | 0.76 | AKR1B1 (0.34) | MEN1KMT2APOLBMALT1EGFR | |
| SCHEMBL8795374 | 0.76 | AKR1B1 (0.34) | MEN1KMT2APOLBMALT1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541807-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1997-12-17 | — | — | EP | disclosed |
| US-5412117-A | Potassium channel activators, antiasmatics, antiepileptics | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0541807-A1 | NOVEL BENZOPYRAN DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 1993-05-19 | — | — | EP | disclosed |