Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795895 | 0.87 | EGFR (0.34) | KMT2AMEN1MAPTALDH1A1ABCC9 | |
| SCHEMBL8795103 | 0.80 | AKR1B1 (0.34) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL8795374 | 0.80 | AKR1B1 (0.34) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL8795010 | 0.80 | EGFR (0.36) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL8793999 | 0.79 | EGFR (0.34) | POLBMAPTALDH1A1ABCC9EGFR | |
| SCHEMBL8795892 | 0.79 | EGFR (0.34) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL8795889 | 0.79 | EGFR (0.34) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL29442980 | 0.79 | EGFR (0.34) | POLBMAPTALDH1A1ABCC9EGFR | |
| SCHEMBL8794980 | 0.76 | ALDH1A1 (0.36) | KMT2AMEN1MAPTALDH1A1EGFR | |
| SCHEMBL8794987 | 0.76 | ALDH1A1 (0.36) | KMT2AMEN1MAPTALDH1A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541807-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1997-12-17 | — | — | EP | disclosed |
| US-5412117-A | Potassium channel activators, antiasmatics, antiepileptics | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0541807-A1 | NOVEL BENZOPYRAN DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 1993-05-19 | — | — | EP | disclosed |