Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR3 | O15455 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8794786 | 0.91 | MEN1 (0.35) | ALDH1A1MAPTL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL8794789 | 0.91 | MEN1 (0.35) | ALDH1A1MAPTL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL8795892 | 0.85 | EGFR (0.34) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8795889 | 0.85 | EGFR (0.34) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8314196 | 0.82 | TLR3 (0.34) | TLR3TLR9TLR8ALDH1A1MAPT | |
| SCHEMBL8316173 | 0.81 | EGFR (0.34) | ALDH1A1MAPTEGFRAKR1B1 | |
| SCHEMBL8313666 | 0.79 | TBXA2R (0.31) | ALDH1A1MAPTMEN1KMT2AEGFR | |
| SCHEMBL8312851 | 0.79 | TLR3 (0.38) | TLR3TLR9TLR8ALDH1A1MAPT | |
| SCHEMBL8313582 | 0.78 | TLR3 (0.38) | TLR3TLR9TLR8ALDH1A1MAPT | |
| SCHEMBL8313587 | 0.77 | L3MBTL1 (0.41) | TLR3TLR9TLR8ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632033-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| US-5646308-A | POTASSIUM CHANNEL ACTIVATORS USED AS ANTIASTHMATICS, ANTIEPILEPTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0632033-A1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-01-04 | — | — | EP | disclosed |