Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL105281 | 0.84 | MAPT (0.51) | ALDH1A1MAPTKMT2ASMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL4345251 | 0.82 | MAPT (0.50) | ALDH1A1MAPTKMT2ASMN1; SMN2POLB | |
| SCHEMBL7635018 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MAPTKMT2APOLBHPGD | |
| SCHEMBL22571328 | 0.81 | MAPT (0.49) | ALDH1A1MAPTKMT2ASMN1; SMN2POLB | |
| SCHEMBL1641491 | 0.81 | MAPT (0.49) | ALDH1A1MAPTKMT2ASMN1; SMN2POLB | |
| SCHEMBL23877938 | 0.79 | MAPT (0.47) | ALDH1A1MAPTKMT2ASMN1; SMN2POLB | |
| SCHEMBL1356510 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTKMT2ASMN1; SMN2POLB | |
| SCHEMBL1356508 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTKMT2ASMN1; SMN2POLB | |
| SCHEMBL17605281 | 0.79 | USP2 (0.49) | ALDH1A1MAPTKMT2ASMN1; SMN2POLB | |
| SCHEMBL13995929 | 0.78 | MAPT (0.46) | ALDH1A1MAPTKMT2ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648768-B1 | Preparation of 3-dihaloacetyl oxazolidines | MONSANTO CO (US) | 1997-11-26 | — | — | EP | disclosed |
| US-5428172-A | Preparation of 3-dihaloacetyl oxazolidines | MONSANTO COMPANY (US) | 1995-06-27 | — | — | US | disclosed |
| EP-0648768-A1 | Preparation of 3-dihaloacetyl oxazolidines | MONSANTO COMPANY (US) | 1995-04-19 | — | — | EP | disclosed |