Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | RGS12 | O14924 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729341 | 0.84 | L3MBTL1 (0.57) | ALDH1A1NPSR1LMNAMAPTL3MBTL1 | |
| SCHEMBL8795665 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MAPTL3MBTL1KDM4EKMT2A | |
| SCHEMBL28318922 | 0.79 | L3MBTL1 (0.66) | ALDH1A1NPSR1LMNAMAPK1MAPT | |
| SCHEMBL7637484 | 0.77 | LMNA (0.79) | ALDH1A1NPSR1LMNAMAPK1HTT | |
| SCHEMBL5270097 | 0.77 | LMNA (0.79) | ALDH1A1NPSR1LMNAMAPK1HTT | |
| SCHEMBL7785516 | 0.77 | LMNA (0.79) | ALDH1A1NPSR1LMNAMAPK1HTT | |
| SCHEMBL9462452 | 0.75 | MAPT (0.70) | ALDH1A1NPSR1LMNAMAPTL3MBTL1 | |
| SCHEMBL9462454 | 0.75 | MAPT (0.70) | ALDH1A1NPSR1LMNAMAPTL3MBTL1 | |
| SCHEMBL105281 | 0.75 | MAPT (0.51) | ALDH1A1MAPTL3MBTL1CYP2D6CYP2C19 | |
| SCHEMBL25455699 | 0.73 | CYP2D6 (0.62) | ALDH1A1NPSR1LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193347-A1 | Using an optically active N-substituted chiral derivative of norephedrine as ligand for enantioselective reduction of unsaturated compounds carrying functional groups by a hydrogen transfer method | PPG-SIPSY, A CORPORATION OF FRANCE (FR) | 2002-12-19 | — | — | US | claimed |
| US-20020193347-A1 | Using an optically active N-substituted chiral derivative of norephedrine as ligand for enantioselective reduction of unsaturated compounds carrying functional groups by a hydrogen transfer method | PPG-SIPSY, A CORPORATION OF FRANCE (FR) | 2002-12-19 | — | — | US | disclosed |