Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 3/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10381355 | 0.88 | ABCB1 (0.35) | ABCC9ABCB1KDM4E | |
| SCHEMBL8794704 | 0.86 | ABCB1 (0.33) | ABCC9ABCB1KDM4EKCNE1KCNQ1 | |
| SCHEMBL8795466 | 0.85 | ALDH1A1 (0.42) | ABCC9ABCB1KDM4EMEN1KMT2A | |
| SCHEMBL10438283 | 0.83 | DHODH (0.36) | ABCC9MEN1KMT2A | |
| SCHEMBL8795220 | 0.82 | ABCC9 (0.34) | ABCC9ABCB1KDM4EMALT1KCNE1 | |
| SCHEMBL10438277 | 0.81 | MAPT (0.41) | KDM4EMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9662677 | 0.79 | ABCC9 (0.36) | ABCC9ABCB1KDM4EMALT1KCNE1 | |
| SCHEMBL8795464 | 0.79 | ABCB1 (0.35) | ABCC9ABCB1KDM4ECYP3A4 | |
| SCHEMBL8795251 | 0.76 | CXCR1 (0.44) | ABCC9ABCB1MEN1KMT2A | |
| SCHEMBL10382337 | 0.76 | ABCB1 (0.34) | ABCC9ABCB1KDM4EKCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990014346-A1 | BENZOPYRAN DERIVATIVES | BEECHAM GROUP PLC (GB) | 1990-11-29 | — | — | WO | claimed |
| EP-0398665-A1 | Benzopyran derivatives | Beecham Group p.l.c. (GB) | 1990-11-22 | — | — | EP | claimed |
| EP-0541807-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1997-12-17 | — | — | EP | disclosed |
| US-5412117-A | Potassium channel activators, antiasmatics, antiepileptics | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0541807-A1 | NOVEL BENZOPYRAN DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 1993-05-19 | — | — | EP | disclosed |
| WO-1990014346-A1 | BENZOPYRAN DERIVATIVES | BEECHAM GROUP PLC (GB) | 1990-11-29 | — | — | WO | disclosed |
| EP-0398665-A1 | Benzopyran derivatives | Beecham Group p.l.c. (GB) | 1990-11-22 | — | — | EP | disclosed |
| EP-0367296-A2 | Ether carboxylate detergent builders | THE PROCTER & GAMBLE COMPANY (US) | 1990-05-09 | — | — | EP | disclosed |
| EP-0357280-A2 | Soil release agents having allylderived sulfonated end caps | THE PROCTER & GAMBLE COMPANY (US) | 1990-03-07 | — | — | EP | disclosed |