Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 1/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.39 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795466 | 0.88 | ALDH1A1 (0.42) | CXCR1CXCR2ABCC9ALDH1A1MAPT | |
| SCHEMBL10381352 | 0.87 | EGFR (0.39) | CXCR1CXCR2EGFRSRCHTT | |
| SCHEMBL10381354 | 0.87 | RXFP1 (0.48) | PLAUALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10381384 | 0.80 | RARA (0.42) | CXCR1CXCR2EGFRSRCHTT | |
| SCHEMBL10382339 | 0.78 | CYP3A4 (0.35) | ABCC9MEN1KMT2AABCB1 | |
| SCHEMBL8795464 | 0.77 | ABCB1 (0.35) | ABCC9ALDH1A1MAPTABCB1 | |
| SCHEMBL10438283 | 0.77 | DHODH (0.36) | ABCC9ALDH1A1MEN1KMT2ABACE1 | |
| SCHEMBL10381374 | 0.76 | ABCB1 (0.36) | ABCC9ABCB1 | |
| SCHEMBL8795220 | 0.76 | ABCC9 (0.34) | ABCC9MEN1KMT2AABCB1 | |
| SCHEMBL8795668 | 0.76 | ABCC9 (0.34) | ABCC9MEN1KMT2AABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990014346-A1 | BENZOPYRAN DERIVATIVES | BEECHAM GROUP PLC (GB) | 1990-11-29 | — | — | WO | claimed |
| EP-0398665-A1 | Benzopyran derivatives | Beecham Group p.l.c. (GB) | 1990-11-22 | — | — | EP | claimed |
| EP-0541807-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1997-12-17 | — | — | EP | disclosed |
| US-5412117-A | Potassium channel activators, antiasmatics, antiepileptics | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0541807-A1 | NOVEL BENZOPYRAN DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 1993-05-19 | — | — | EP | disclosed |
| WO-1990014346-A1 | BENZOPYRAN DERIVATIVES | BEECHAM GROUP PLC (GB) | 1990-11-29 | — | — | WO | disclosed |
| EP-0398665-A1 | Benzopyran derivatives | Beecham Group p.l.c. (GB) | 1990-11-22 | — | — | EP | disclosed |