Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 7/20 | 0.43 |
| ▸ | RXRB | P28702 | 6/20 | 0.43 |
| ▸ | RXRG | P48443 | 5/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8794923 | 0.90 | S1PR1 (0.43) | SMN1; SMN2S1PR1OPRD1SLC2A1NPSR1 | |
| SCHEMBL8873450 | 0.86 | RXRA (0.41) | RXRARXRBRXRGHCRTR1HCRTR2 | |
| SCHEMBL8795541 | 0.84 | SLC2A1 (0.49) | HCRTR1HCRTR2SMN1; SMN2S1PR1OPRD1 | |
| SCHEMBL8795503 | 0.82 | LMNA (0.45) | RXRARXRBRXRGSMN1; SMN2NPSR1 | |
| SCHEMBL8794120 | 0.81 | KMT2A (0.39) | SMN1; SMN2S1PR1OPRD1SLC2A1NPSR1 | |
| SCHEMBL8795781 | 0.80 | ALDH1A1 (0.43) | RXRARXRBRXRGSMN1; SMN2NPSR1 | |
| SCHEMBL8795729 | 0.79 | ALDH1A1 (0.38) | RXRARXRBRXRGNPSR1ALDH1A1 | |
| SCHEMBL8634474 | 0.78 | EDNRB (0.39) | RXRARXRBRXRGSMN1; SMN2S1PR1 | |
| SCHEMBL8626603 | 0.77 | RXRA (0.41) | RXRARXRBRXRGSMN1; SMN2NPSR1 | |
| SCHEMBL1111522 | 0.73 | POLB (0.47) | SMN1; SMN2NPSR1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0645386-B1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1997-12-29 | — | — | EP | disclosed |
| EP-0645386-A1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1995-03-29 | — | — | EP | disclosed |