Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 3/20 | 0.44 |
| ▸ | RARB | P10826 | 6/20 | 0.32 |
| ▸ | RARG | P13631 | 5/20 | 0.32 |
| ▸ | RARA | P10276 | 5/20 | 0.32 |
| ▸ | RXRA | P19793 | 3/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795773 | 1.00 | PLA2G4A (0.44) | PLA2G4ARARBRARGRARARXRA | |
| SCHEMBL8796491 | 0.92 | RARG (0.38) | PLA2G4ARARBRARGRARARXRA | |
| SCHEMBL8796493 | 0.92 | RARG (0.38) | PLA2G4ARARBRARGRARARXRA | |
| SCHEMBL8796886 | 0.87 | PLA2G4A (0.45) | PLA2G4ARARBRARGRARA | |
| SCHEMBL8796891 | 0.87 | PLA2G4A (0.45) | PLA2G4ARARBRARGRARA | |
| SCHEMBL8796153 | 0.82 | PLA2G4A (0.51) | PLA2G4ARARBRARGRARARXRA | |
| SCHEMBL8796157 | 0.82 | PLA2G4A (0.51) | PLA2G4ARARBRARGRARARXRA | |
| SCHEMBL8795690 | 0.79 | KMT2A (0.36) | — | |
| SCHEMBL8795697 | 0.79 | KMT2A (0.36) | — | |
| SCHEMBL8796246 | 0.78 | RARA (0.41) | PLA2G4ARARBRARGRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629604-B1 | Alicyclic phospholipase A2 inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1997-04-16 | — | — | EP | disclosed |
| US-5436369-A | Alicyclic phospholipase A2 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-07-25 | — | — | US | disclosed |