Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27866763 | 0.85 | ESR1 (0.54) | ESR1KDM4ETBXAS1 | |
| SCHEMBL491657 | 0.83 | KDM4E (0.55) | KDM4E | |
| SCHEMBL1070542 | 0.83 | CYP11B1 (0.55) | KDM4ETSHRTBXAS1 | |
| SCHEMBL10289405 | 0.81 | TSHR (0.57) | KDM4ETSHRTBXAS1 | |
| SCHEMBL2536496 | 0.81 | KMT2A (0.54) | TSHRTBXAS1 | |
| SCHEMBL7388461 | 0.81 | TBXAS1 (0.56) | TBXAS1 | |
| SCHEMBL25168671 | 0.80 | TSHR (0.59) | KDM4ETSHRTBXAS1 | |
| SCHEMBL6960220 | 0.80 | TSHR (0.59) | KDM4ETSHRTBXAS1 | |
| SCHEMBL14034743 | 0.80 | TSHR (0.59) | KDM4ETSHRTBXAS1 | |
| SCHEMBL6957299 | 0.80 | TSHR (0.59) | KDM4ETSHRTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758653-A1 | IMIDAZOQUINAZOLINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-02-19 | — | — | EP | disclosed |