Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 5/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CDH1 | P12830 | 1/20 | 0.41 |
| ▸ | APC | P25054 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712382 | 0.83 | RAB9A (0.48) | SRD5A2NR4A1MEN1KMT2AALDH1A1 | |
| SCHEMBL9712369 | 0.83 | MDM2 (0.47) | SRD5A2NR4A1MEN1KMT2AMAPK1 | |
| SCHEMBL3154810 | 0.82 | ALDH1A1 (0.52) | SRD5A2NR4A1ALOX15MEN1KMT2A | |
| SCHEMBL6977856 | 0.82 | KDM4E (0.53) | SRD5A2KDM4EMEN1KMT2APOLB | |
| SCHEMBL9712544 | 0.82 | NR4A1 (0.50) | SRD5A2NR4A1KDM4EMEN1KMT2A | |
| SCHEMBL7293957 | 0.81 | KDM4E (0.48) | SRD5A2TSHRKDM4EALDH1A1POLB | |
| SCHEMBL28775847 | 0.80 | KDM4E (0.73) | SRD5A2NR4A1TSHRALOX15KDM4E | |
| SCHEMBL10934884 | 0.79 | POLB (0.68) | MEN1KMT2AALDH1A1MAPK1RAB9A | |
| SCHEMBL9130311 | 0.78 | NR4A1 (0.61) | SRD5A2NR4A1KDM4EMEN1KMT2A | |
| SCHEMBL9712508 | 0.77 | GAA (0.49) | SRD5A2MEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810209-A2 | Alpha - and beta-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 1997-12-03 | — | — | EP | disclosed |