Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11456649 | 0.83 | RAB9A (0.68) | KMT2ARAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8298007 | 0.81 | RAB9A (0.79) | KMT2ARAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL4903484 | 0.81 | RAB9A (0.65) | KMT2ARAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL16718938 | 0.81 | RAB9A (0.65) | KMT2ARAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8486609 | 0.80 | KMT2A (0.67) | KMT2ARAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8486911 | 0.80 | ALDH1A1 (0.56) | KMT2ARAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8795174 | 0.80 | RAB9A (0.63) | KMT2ARAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL10050510 | 0.79 | RAB9A (0.85) | KMT2ARAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL5631833 | 0.79 | RAB9A (0.77) | KMT2ARAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL10603852 | 0.79 | KMT2A (0.70) | KMT2ARAB9AMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792873-A1 | N-(Phenoxyalkyl) carboxamides and their use as antiarrhythmic agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | disclosed |