Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797206 | 0.96 | HRH3 (0.38) | FFAR1PPARGMAOBHRH3PSEN1 | |
| SCHEMBL8797111 | 0.91 | HRH3 (0.35) | FFAR1PPARGHRH3 | |
| SCHEMBL8797133 | 0.90 | HRH3 (0.34) | FFAR1PPARGHRH3 | |
| SCHEMBL8797688 | 0.90 | HRH3 (0.35) | FFAR1PPARGHRH3 | |
| SCHEMBL8797138 | 0.90 | HRH3 (0.34) | FFAR1PPARGHRH3 | |
| SCHEMBL8797588 | 0.90 | DRD2 (0.36) | MAOBHRH3KCNH2MCHR1 | |
| SCHEMBL8797429 | 0.89 | MAOB (0.35) | FFAR1PPARGMAOBHRH3 | |
| SCHEMBL8796803 | 0.89 | HTT (0.36) | HRH3 | |
| SCHEMBL8797027 | 0.88 | HRH3 (0.36) | FFAR1PPARGMAOBHRH3 | |
| SCHEMBL8797744 | 0.88 | HRH3 (0.35) | FFAR1PPARGMAOBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |