Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.31 |
| ▸ | PPARG | P37231 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797974 | 0.96 | HRH3 (0.37) | MAOBHRH3GRM5 | |
| SCHEMBL8796797 | 0.89 | FFAR1 (0.39) | MAOBHRH3FFAR1PPARG | |
| SCHEMBL8797588 | 0.89 | DRD2 (0.36) | MAOBHRH3GRM5MAOASMN1; SMN2 | |
| SCHEMBL8797688 | 0.89 | HRH3 (0.35) | HRH3FFAR1PPARGMAPTSMN1; SMN2 | |
| SCHEMBL8797138 | 0.89 | HRH3 (0.34) | HRH3FFAR1PPARG | |
| SCHEMBL8797133 | 0.89 | HRH3 (0.34) | HRH3FFAR1PPARG | |
| SCHEMBL8796803 | 0.88 | HTT (0.36) | HRH3MAPTSMN1; SMN2KMT2A | |
| SCHEMBL8797111 | 0.87 | HRH3 (0.35) | HRH3TNIKFFAR1PPARG | |
| SCHEMBL8797027 | 0.87 | HRH3 (0.36) | MAOBHRH3FFAR1PPARGMAPT | |
| SCHEMBL8797744 | 0.87 | HRH3 (0.35) | MAOBHRH3FFAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |