Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.37 |
| ▸ | HRH2 | P25021 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797039 | 0.96 | KDM4E (0.34) | HRH3HRH2HRH1KDM4EL3MBTL1 | |
| SCHEMBL8797173 | 0.89 | HRH3 (0.33) | HRH3 | |
| SCHEMBL8797206 | 0.87 | HRH3 (0.38) | HRH3L3MBTL1KDM4AUSP2POLB | |
| SCHEMBL8796918 | 0.87 | HRH3 (0.38) | HRH3L3MBTL1KMT2AKDM4AUSP2 | |
| SCHEMBL8797974 | 0.87 | HRH3 (0.37) | HRH3HRH2HRH1MEN1DRD2 | |
| SCHEMBL8797244 | 0.86 | HRH3 (0.52) | HRH3MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL8798105 | 0.85 | HRH3 (0.44) | HRH3L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8796841 | 0.85 | HRH3 (0.39) | HRH3L3MBTL1MEN1MAPTRAB9A | |
| SCHEMBL8797688 | 0.85 | HRH3 (0.35) | HRH3L3MBTL1GAAMEN1MAPT | |
| SCHEMBL8797269 | 0.85 | HRH3 (0.35) | HRH3KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |