Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698725 | 0.81 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL8796975 | 0.78 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL9206986 | 0.76 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL8708001 | 0.74 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL7832608 | 0.73 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8796884 | 0.72 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL2095690 | 0.72 | MBNL1 (0.44) | — | |
| SCHEMBL7844228 | 0.71 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL7840996 | 0.71 | ALOX5 (0.49) | PTGS2PTGS1 | |
| SCHEMBL3801351 | 0.71 | PTGS2 (0.63) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772606-A1 | SUBSTITUTED THIAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996003392-A1 | SUBSTITUTED THIAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-02-08 | — | — | WO | disclosed |