Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTC4S | Q16873 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528291 | 0.78 | ALDH1A1 (0.39) | TNFCNR1ALDH1A1HPGDCDC25B | |
| SCHEMBL17348086 | 0.74 | TNF (0.46) | LTC4STNFCNR1ALDH1A1HPGD | |
| SCHEMBL8529950 | 0.70 | PRNP (0.40) | ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8530427 | 0.70 | ALDH1A1 (0.39) | ALDH1A1HPGDCYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL7896766 | 0.69 | ALDH1A1 (0.47) | LTC4SALDH1A1HPGDCDC25BKMT2A | |
| SCHEMBL7832871 | 0.68 | TNF (0.48) | LTC4STNFCNR1ALDH1A1HPGD | |
| SCHEMBL25156303 | 0.68 | KMT2A (0.52) | LTC4SALDH1A1HPGDCDC25BSMN1; SMN2 | |
| SCHEMBL15203285 | 0.68 | KMT2A (0.52) | LTC4SALDH1A1HPGDCDC25BSMN1; SMN2 | |
| SCHEMBL31360448 | 0.68 | KMT2A (0.52) | LTC4SALDH1A1HPGDCDC25BSMN1; SMN2 | |
| SCHEMBL8764852 | 0.68 | PRNP (0.57) | ALDH1A1HPGDPRNPRXFP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807114-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1997-11-19 | — | — | EP | disclosed |