Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530427 | 0.88 | ALDH1A1 (0.39) | PRNPRXFP1KMT2AMAPTALDH1A1 | |
| SCHEMBL8764852 | 0.82 | PRNP (0.57) | PRNPRXFP1KMT2AMEN1MAPT | |
| SCHEMBL8528291 | 0.82 | ALDH1A1 (0.39) | PRNPRXFP1KMT2AMEN1MAPT | |
| SCHEMBL9067733 | 0.74 | CAPN1 (0.44) | PRNPGAARXFP1KMT2AMEN1 | |
| SCHEMBL6345753 | 0.73 | CNR2 (0.53) | PRNPGAAKMT2AMEN1MAPT | |
| SCHEMBL1269611 | 0.72 | MEN1 (0.59) | PRNPGAARXFP1KMT2AMEN1 | |
| SCHEMBL7368226 | 0.71 | CNR2 (0.57) | PRNPGAAKMT2AMEN1MAPT | |
| SCHEMBL8528852 | 0.71 | L3MBTL1 (0.44) | PRNPGAARXFP1KMT2AALDH1A1 | |
| SCHEMBL8797019 | 0.70 | LTC4S (0.39) | PRNPRXFP1KMT2AMEN1CYP3A4 | |
| SCHEMBL7050341 | 0.70 | CYP3A4 (0.39) | GAAMAPTCNR2ANPEPEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773428-A | BONE DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1998-06-30 | — | — | US | disclosed |
| EP-0726903-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX INC (US) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012603-A1 | MATRIX METALLOPROTEASE INHIBITORS________________________________ | SYNTEX (U.S.A.) INC. (US) | 1995-05-11 | — | — | WO | disclosed |